5 WORLD GASTROENTEROLOGY NEWS APRIL 2015 Editorial | Expert Point of View | Gastro 2015: AGW/WGO | WDHD News | WGO & WGOF News | WGO Global Guidelines | Calendar of Events no family history of IBD. All patients and controls were interviewed by the same researcher about the countries where they lived before being diagnosed with IBD and for how long they stayed in those countries. We found that people who migrated to Western Europe had a higher risk of developing IBD than people remaining in Spain. These data showed for the first time the association of IBD with migration within Europe. In contrast, people who migrated to Latin America, and thus to less or similarly industrialized countries than Spain, did not have an increased the risk of developing IBD. A relevant finding in our study was that people who migrated to Western European countries had an especially high risk for UC compared to CD. Once again, the etiologies of CD and UC seem to be different, with genetic factors being more important in CD and environmental factors being possibly more relevant in UC. All these studies support the role of environmental factors in the etiopathogenesis of IBD. They also underline the relevance of a globalized world in modifying the epidemiology of diseases in which environment plays a role. Future research should focus on specific environmental factors related to industrialization and development that can play a role in the etiopathogenesis of IBD, and to what extent public health initiatives aimed at modifying them may reduce the risk of these diseases. References 1. Ananthakrishnan AN, McGinley EL, Binion DG, Saeian K. Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis. Inflamm Bowel Dis. 2011;17:1138- 45. 2. Probert CS, Jayanthi V, Pollock DJ, Baithun SI, Mayberry JF, Rampton DS. Crohn’s disease in Bangladeshis and Europeans in Britain: an epidemiological comparison in Tower Hamlets. Postgrad Med J. 1992;68:914-20. 3. Carr I, Mayberry JF. The effects of migration on ulcerative colitis: a three-year prospective study among Europeans and first- and second- generation South Asians in Leicester (1991-1994). Am J Gastroenterol. 1999;94:2918-22. 4. Damas OM, Jahann DA, Reznik R, McCauley JL, Tamariz L, Deshpande AR, et al. Phenotypic manifestations of inflammatory bowel disease differ between Hispanics and non-Hispanic whites: results of a large cohort study. Am J Gastroenterol. 2013;108:231-9. 5. Pinsk V, Lemberg DA, Grewal K, Barker CC, Schreiber RA, Jacobson K. Inflammatory bowel disease in the South Asian pediatric population of British Columbia. Am J Gastroenterol. 2007;102:1077-83. 6. Barreiro-de Acosta M, Alvarez Castro A, Souto R, Iglesias M, Lorenzo A, Dominguez-Muñoz JE. Emigration to western industrialized countries: A risk factor for developing inflammatory bowel disease. J Crohns Colitis. 2011;5:566-9.
ewgn-vol20-issue1-FINAL
To see the actual publication please follow the link above